Protein Residue pKa Prediction by P-SPOC

Predicted pKa Value:


  1. Upload your protein structure file(.pdb)
  2. Fill "Chain ID" with one uppercase character
  3. Fill "Residue Type" with three uppercase characters which represent residue type. Now "LYS", "HIS", "GLU", "ASP", "TYR", "CYS" were supported
  4. Fill "Residue Index" with a integer of the predicted residue index in sequence. The index of residue should be consistant with your uploaded file in step 1
  5. Click "Start" and wait for a moment
  6. The prediction will show at the buttom


  1. For more information, visit our GitHub repository: PSPOC Version 1.0 on GitHub